Human-induced climate change, in conjunction with environmental degradation, will have unavoidable effects on cities. UN-Habitat estimates that 70% of the world’s population will live in urban areas by 2050, and approximately 60% of the growth is expected to take place in Asia. Climate change will lead to warmer temperatures, greater variability in local conditions, and changes in the frequency, intensity, and location of precipitation and storms. Mediumsized cities are growing particularly rapidly and lack the resources of larger, more established cities to address the compounding challenges of climate change, urbanization, poverty, and environmental degradation. How will these cities manage the stresses and respond to the inevitable shocks and surprises of climate change while assuring the wellbeing of their growing populations?